![]() Set of related objects, using an a prefix: aadd(), Related managers now provide asynchronous versions of methods that change a. ![]() Model now provides asynchronous versions of some methods that use the.F() expressions that output BooleanFieldĬan now be negated using ~F() (inversion operator).On MySQL and millisecond precision on SQLite. The text value of a key, index, or path transform of The new robust argument for on_commit()Īllows performing actions that can fail after a database transaction is.Window functions with the exception of disjunctive filter lookupsĪgainst window functions when performing aggregation. QuerySet now extensively supports filtering against.If it is not PCa, and I hope that it is not, then nothing is lost except a bit of effort and time for ruling it out. ![]() I write this not to worry you but we wish that we had acted sooner than we did instead of relying on the urologist to tell us not to worry about anything. Dr Walsh's book says that this should not be done unless something shows that there is an antibiotic infection. Our urologist gave a 30 day antibiotic course for PSA rises instead of further tests. He suggests a range of 2.5 to 3 to strike a reasonable balance between early detection and overdiagnosis. This landmark study suggests that free PSA percentage may be an excellent predictor of aggressive tumours that will need to be treated." According to Dr Walsh between the ages 50-59, only 3% men have PSA between 4.1 - 9.9. Men with slower growing, nonaggressive cancer all had free PSA levels greater than 15%. and found that fifteen years before cancer was diagnosed, all the men who turned out to have aggressive prostate tumours had levels of free PSA that were lower than 15%. Johns Hopkins study using the large database. evidence shows that free PSA can predict which tumours will be aggressive - and need to be treated as soon as possible. if the free PSA is less than 10%, it's more likely that most of that PSA is coming from cancer, that the caner is significant in size, and that it will prove aggressive. Several large studies showed that men who had a PSA velocity of 2 within the year before diagnosis were much more likely to have an aggressive form of caner. Clearly, something is going on here.If you have a PSA level between 1 and 4 and it is consistently rising faster than approx 0.4 ng/ml a year, you should get a biopsy. Say that over eighteen months, a man's PSA level went up from 4.0 to 4.6 to 5.8 ng/ml. įor men with PSAs greater than 4, an average, consistent increase of more than 0.75 ng/ml over the course of three tests is considered significant. ![]() You can proceed directly to biopsy or consider a second line test to help determine if a biopsy is really necessary.what matters is a significant change over time. Also, get a free PSA check done.ĭr Walsh "If your PSA level is above 3 or you have a prostate exam with a suspicious lump or hard spot you need additional testing. He gives various indications for alarm bells to ring. Without wishing to alarm you, I wish that I had read Dr Walsh's book as soon as the first small PSA test came back at 4.1 or something. Almost a year went by before biopsy was ordered. Never asked about the history of cancer in the family. Our urologist kept telling us not to worry and that PCa is the slowest cancer there etc. Keep watch and do the relevant testing, he has time but not to wait until it comes a bigger problem. The side effects are hot flashes, some tiredness and weight gain along with elevated blood pressure but at 70 I feel good and plan on being around for a long time. I feel good still work part time, when life throws lemons at you you try to make lemonade. I did cut red meat to once a week, lots of fish, chicken, turkey only 3 eggs a week but kept dairy products. PSA still under 1 and stable, gained about 35 pounds due to the medicine but my BMI is normal due to my height. 6, gained weight and started another line if defense last December. Then the readings came in at 156 and had a biopsy done to find it was a Gleason 9, stage 4 that had spread to the bone in 4 places, went to an oncologist and started ADT with chemo which went well, PSA dropped to. Just my personal experience, my number in my early 60s was 5,4 with no symptoms, then went to 7.4 for a year with no symptoms, then at 66 I developed urinary issues and lost about 5 pounds.
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